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低级别颅底软骨肉瘤接受高剂量质子 - 光子放射治疗后发生的间变性胶质瘤。

Anaplastic glioma after high-dose proton-photon radiation treatment for low-grade skull base chondrosarcoma.

作者信息

Ehsani Sepehr, Hodaie Mojgan, Liebsch Norbert J, Gentili Fred, Kiehl Tim-Rasmus

机构信息

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

出版信息

J Neurooncol. 2008 Jun;88(2):231-6. doi: 10.1007/s11060-008-9560-2.

DOI:10.1007/s11060-008-9560-2
PMID:18345517
Abstract

We report the case of a 63-year-old man who developed an anaplastic oligoastrocytoma of the brain stem and midbrain 13 years after postoperative high-dose proton-photon radiation therapy for a recurrent low-grade chondrosarcoma of the skull base. To our knowledge, this is the first reported case of an anaplastic glioma after proton-photon irradiation.

摘要

我们报告了一例63岁男性患者的病例，该患者在因复发性颅底低级别软骨肉瘤接受术后高剂量质子 - 光子放射治疗13年后，发生了脑干和中脑间变性少突星形细胞瘤。据我们所知，这是首例报道的质子 - 光子照射后发生间变性胶质瘤的病例。

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Anaplastic glioma after high-dose proton-photon radiation treatment for low-grade skull base chondrosarcoma.低级别颅底软骨肉瘤接受高剂量质子 - 光子放射治疗后发生的间变性胶质瘤。
J Neurooncol. 2008 Jun;88(2):231-6. doi: 10.1007/s11060-008-9560-2.
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Temporal lobe (TL) damage following surgery and high-dose photon and proton irradiation in 96 patients affected by chordomas and chondrosarcomas of the base of the skull.96例颅底脊索瘤和软骨肉瘤患者术后及接受高剂量光子和质子照射后出现颞叶（TL）损伤。
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本文引用的文献

1
Sarcoma arising in irradiated bone; report of 11 cases.放疗后骨组织发生的肉瘤；11例报告
Cancer. 1948 May;1(1):3-29. doi: 10.1002/1097-0142(194805)1:1<3::aid-cncr2820010103>3.0.co;2-7.
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Clinicopathologic aspects of 1p/19q loss and the diagnosis of oligodendroglioma.1p/19q缺失的临床病理特征与少突胶质细胞瘤的诊断
Arch Pathol Lab Med. 2007 Feb;131(2):242-51. doi: 10.5858/2007-131-242-CAOQLA.
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Diffuse high-grade gliomas as second malignant neoplasms after radio-chemotherapy for pediatric malignancies.弥漫性高级别胶质瘤作为儿童恶性肿瘤放化疗后的第二原发性恶性肿瘤。
Childs Nerv Syst. 2007 Feb;23(2):185-93. doi: 10.1007/s00381-006-0199-z. Epub 2006 Oct 5.
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Chondrosarcoma of the skull base: long-term follow-up.颅底软骨肉瘤：长期随访
Otol Neurotol. 2006 Oct;27(7):981-91. doi: 10.1097/01.mao.0000233812.48800.b4.
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Radiation-induced spinal glioblastoma multiforme.
Acta Oncol. 2006;45(1):87-90. doi: 10.1080/02841860500341124.
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Is the risk for secondary cancers after proton therapy enhanced distal to the Planning Target Volume? A two-case report with possible explanations.质子治疗后继发癌症的风险在计划靶区远端是否会增加？一份有可能解释的双病例报告。
Radiat Environ Biophys. 2006 May;45(1):39-43. doi: 10.1007/s00411-006-0034-7. Epub 2006 Feb 7.
7
Radiation-induced osteosarcoma 16 years after surgery and radiation for glioma--case report.胶质瘤手术后放疗16年后发生放射性骨肉瘤——病例报告
Neurol Med Chir (Tokyo). 2006 Jan;46(1):51-4. doi: 10.2176/nmc.46.51.
8
Radiation induced meningioma with a short latent period following high dose cranial irradiation - case report and literature review.高剂量颅脑照射后潜伏期短的放射性诱发脑膜瘤——病例报告及文献综述
J Neurooncol. 2006 Mar;77(1):73-7. doi: 10.1007/s11060-005-9009-9. Epub 2005 Nov 15.
9
Chordomas of the base of the skull and upper cervical spine. One hundred patients irradiated by a 3D conformal technique combining photon and proton beams.颅底和上颈椎脊索瘤。100例患者接受了光子束和质子束相结合的三维适形技术照射。
Acta Oncol. 2005;44(7):700-8. doi: 10.1080/02841860500326257.
10
Proton beam therapy.质子束疗法
Br J Cancer. 2005 Oct 17;93(8):849-54. doi: 10.1038/sj.bjc.6602754.