Emons G
Universitäts-Frauenklinik, Robert-Koch-Strasse 40, 37075, Göttingen, Deutschland.
Internist (Berl). 2008 May;49(5):553-8. doi: 10.1007/s00108-008-2107-y.
Hormone therapy with estrogens (combined with progestin for women who have not been hysterectomized) is the most efficacious treatment for climacteric symptoms. A few years ago hormone therapy was considered to be an ideal prevention for cardio-vascular disease, osteoporosis, dementia and other diseases. Large prospective randomized trials have changed this paradigm. Hormone therapy should only be used with a clear indication (moderate to severe climacteric symptoms and - with limitations - prevention of osteoporosis). The lowest effective dose should be used for the shortest possible time.
雌激素激素疗法（对于未进行子宫切除的女性联合使用孕激素）是治疗更年期症状最有效的方法。几年前，激素疗法被认为是预防心血管疾病、骨质疏松症、痴呆症和其他疾病的理想方法。大型前瞻性随机试验改变了这一模式。激素疗法仅应在有明确指征（中度至重度更年期症状以及——有一定限制——预防骨质疏松症）时使用。应使用最低有效剂量，并尽可能缩短使用时间。
