Suter Michel, Giusti Vittorio, Calmes Jean-Marie, Paroz Alexandre
Department of Surgery, Hôpital du Chablais, Aigle-Monthey, 1860 Aigle, Switzerland.
Obes Surg. 2008 May;18(5):578-82. doi: 10.1007/s11695-007-9341-6.
Gastric banding (GB) is one of the most popular bariatric procedures for morbid obesity. Apart from causing weight loss by alimentary restriction, it can interfere with functions of the esophagus and upper stomach. The aim of this study was to evaluate if the results of extensive preoperative upper GI testing were correlated with long-term outcome and complications after GB.
Using a prospectively maintained computerized database including all the patients undergoing bariatric operations in both our hospitals, we performed a retrospective analysis of the patients who underwent complete upper gastrointestinal (GI) testing (endoscopy, pH monitoring, and manometry) before GB.
One hundred thirty-four patients underwent complete testing before GB. Abnormal pH monitoring (increased total reflux time, increased diurnal reflux time, increased number of reflux episodes) predicted the development of complications and especially pouch dilatation and food intolerance. The mean De Meester score was higher among patients who developed complications than in the remaining ones (25.4 vs 17.7, P=0.03). High lower esophageal sphincter pressure also predicted progressive long-term food intolerance. Endoscopic findings were not predictive of the long-term outcome.
There is some association between the function of the upper digestive tract and long-term complications after gastric banding. Abnormal pH monitoring predicts overall long-term complications, especially food intolerance with or without reflux, and pouch dilatation, and a high lower esophageal sphincter pressure predicts long-term food intolerance. Extended upper gastrointestinal testing with endoscopy, 24-h pH monitoring, and esophageal manometry is probably worthwhile in selecting patients for gastric banding.
胃束带术(GB)是治疗病态肥胖最常用的减肥手术之一。除了通过限制饮食导致体重减轻外,它还会干扰食管和胃上部的功能。本研究的目的是评估术前广泛的上消化道检查结果是否与胃束带术后的长期疗效和并发症相关。
利用前瞻性维护的计算机数据库,该数据库包含了我们两家医院所有接受减肥手术的患者,我们对在胃束带术前接受了完整上消化道(GI)检查(内镜检查、pH监测和测压)的患者进行了回顾性分析。
134例患者在胃束带术前接受了完整检查。pH监测异常(总反流时间增加、日间反流时间增加、反流发作次数增加)预示着并发症的发生,尤其是胃囊扩张和食物不耐受。发生并发症的患者的平均De Meester评分高于其余患者(25.4对17.7,P=0.03)。食管下括约肌压力高也预示着长期进行性食物不耐受。内镜检查结果不能预测长期疗效。
上消化道功能与胃束带术后长期并发症之间存在一定关联。pH监测异常预示着总体长期并发症,尤其是有或无反流的食物不耐受以及胃囊扩张,而食管下括约肌压力高预示着长期食物不耐受。在内镜检查、24小时pH监测和食管测压的基础上进行扩展的上消化道检查,对于选择接受胃束带术的患者可能是有价值的。