Hamada Hideo, Kurimoto Masanori, Hayashi Nakamasa, Nagai Shoichi, Kurosaki Kunikazu, Nomoto Kazuhiro, Kanegane Hirokazu, Nomura Keiko, Endo Shunro
Department of Neurosurgery, Faculty of Medicine, University of Toyama, Japan.
J Neurosurg Pediatr. 2008 Mar;1(3):244-6. doi: 10.3171/PED/2008/1/3/244.
The authors report on a rare case of pilomyxoid astrocytoma in a patient presenting with fatal hemorrhage. This 5-year-old boy presented to the outpatient clinic with headache and vomiting. Computed tomography and magnetic resonance imaging studies revealed a mass lesion with partial hemorrhage in the suprasellar region extending into the third ventricle. Partial resection via a transcallosal approach was performed. Because the pathological diagnosis was pilomyxoid astrocytoma, chemotherapy was administered. However, 4 months after the first operation, during chemotherapy, the boy presented with massive intratumoral and intraventricular hemorrhage with hydrocephalus. Although emergent external ventricular drainage was performed, the patient died. In this report, the authors review the literature and discuss the clinical features and treatment of pilomyxoid astrocytoma.
作者报告了一例罕见的毛黏液样星形细胞瘤病例，该患者出现致命性出血。这名5岁男孩因头痛和呕吐到门诊就诊。计算机断层扫描和磁共振成像研究显示，鞍上区域有一个伴有部分出血的肿块病变，延伸至第三脑室。通过经胼胝体入路进行了部分切除术。由于病理诊断为毛黏液样星形细胞瘤，因此给予了化疗。然而，首次手术后4个月，在化疗期间，男孩出现了肿瘤内和脑室内大量出血并伴有脑积水。尽管进行了紧急脑室外引流，但患者仍死亡。在本报告中，作者回顾了文献并讨论了毛黏液样星形细胞瘤的临床特征和治疗方法。
