Inskip H M, Hall A J, Chotard J, Loik F, Whittle H
International Agency for Research on Cancer, MRC Laboratories, Fajara, Nr Banjul, The Gambia.
Int J Epidemiol. 1991 Sep;20(3):764-9. doi: 10.1093/ije/20.3.764.
Data on over a thousand Gambian children have been analysed to examine factors influencing their antibody levels following immunization with hepatitis B vaccine administered during the first year of life. The dominant effect was the time between the last dose of vaccine and taking the blood sample. There was considerable variation in vaccine response by area of residence which could not be explained by any other factor. The hepatitis B surface antigen (HBsAg) status of the mother and the age at vaccination did not appear to have an effect, but there was some indication that a delay in receiving the second dose of vaccine led to a marginally lower response.
对一千多名冈比亚儿童的数据进行了分析，以研究影响他们在出生后第一年接种乙肝疫苗后抗体水平的因素。主要影响因素是最后一剂疫苗接种与采集血样之间的时间。居住地区的疫苗反应存在相当大的差异，无法用任何其他因素来解释。母亲的乙肝表面抗原（HBsAg）状态和接种疫苗时的年龄似乎没有影响，但有迹象表明，第二剂疫苗接种延迟导致反应略低。
