Lawan A
Department of Ophthalmology, Faculty of Medicine, Bayero University Kano, Nigeria.
Ann Afr Med. 2007 Dec;6(4):180-5. doi: 10.4103/1596-3519.55700.
Primary open angle glaucoma (POAG) is one of the leading causes of avoidable blindness. Unlike blindness from cataracts, glaucomatous optic nerve damage is irreversible, and prevention of glaucoma is one of the priorities of World Health Organization (WHO) Vision 2020 program. POAG is the commonest type of glaucoma and affects about 33.1 million people worldwide. This study is a five year review of 71 eyes of 63 patients who had trabeculectomy. The study evaluates the pattern of presentation and modality of surgical treatment in our environment.
Records of all patients with primary open angle glaucoma operated over a five year period was retrieved. Information extracted included patients bio data, visual acuity, gonioscopic findings, intra ocular pressure as measured with applanation tonometer before and after surgery, and recorded in mmHg. Perimetry was done with 2 m tangent screen and recorded in a perimetry chart. All the patients had trabeculectomy with application of antimetabolite (5-fluorouracil). Extra capsular cataract extraction with or, without posterior chamber intra ocular lens implantation was done on 13 patients. Biometry was not done on patients with cataract. Surgery was done on better eye first in all patients.
There were 71 eyes of 63 patients. The male to female ratio was 3:1. The age ranged between 18 to 75 years. 8 patients were below the age of 30 years. One third of the patients were between the ages of 50 to 59 years. At presentation 12 patients (19%) had normal vision (WHO vision category O), 26 patients (41%) were visually impaired, 12 patients (19%) were severely visually impaired and 13 patients (21%) were blind (from co existing cataracts). The cup disc(c: d) ratio assessed before surgery was 0.5 in 9 eyes (13%), 31 eyes (53%) had c: d ratio 0.6 to 0.8 and 18 eyes had c: d ratio of 0.9. All the patients had open anterior chamber angles (Schafer grade 3 and 4). Perimetric changes were; mild peripheral constriction in 5 eyes (8%), peripheral constriction with arcuate scotoma in 19 eyes (26%), constricted fields of 300 or less in 34 eyes (48%), and in 13 eyes there was inability to fixate on target. IOP before surgery was 21 to 30 mm Hg in 12 eyes (17%), and above 31 mm Hg in 69 eyes (83%). Post operative IOP of 10 to 15 mm Hg was obtained in 58 eyes (82%) and 11 eyes (15%) had IOP of 16 to 20 mm Hg. Only 2 eyes (3%) had IOP in the lower twenties.
Primary open angle glaucoma is characterized by late presentation. Trabeculectomy with application of 5FU is the surgical treatment of choice in our environment and give good intra ocular pressure control. There is need to increase public awareness on glaucoma to limit this type of avoidable blindness.
原发性开角型青光眼(POAG)是可避免失明的主要原因之一。与白内障导致的失明不同,青光眼性视神经损伤是不可逆的,预防青光眼是世界卫生组织(WHO)“视觉2020”计划的重点之一。POAG是最常见的青光眼类型,全球约有3310万人受其影响。本研究是对63例行小梁切除术患者的71只眼进行的为期五年的回顾性研究。该研究评估了我们所在地区患者的临床表现模式和手术治疗方式。
检索了五年内所有原发性开角型青光眼手术患者的记录。提取的信息包括患者的生物数据、视力、前房角镜检查结果、手术前后用压平眼压计测量的眼压(单位为mmHg),并记录在视野计图表中。所有患者均行小梁切除术并应用抗代谢药物(5-氟尿嘧啶)。13例患者行白内障囊外摘除术,部分患者植入或未植入后房型人工晶状体。白内障患者未进行生物测量。所有患者均先对较好的眼进行手术。
63例患者共71只眼。男女比例为3:1。年龄在18至75岁之间。8例患者年龄低于30岁。三分之一的患者年龄在50至59岁之间。就诊时,12例患者(占19%)视力正常(WHO视力分级O级),26例患者(占41%)视力受损,12例患者(占19%)严重视力受损,13例患者(占21%)失明(因合并白内障)。术前评估的杯盘比(c:d),9只眼(占13%)为0.5,31只眼(占53%)为0.6至0.8,18只眼为0.9。所有患者前房角均开放(Shaffer分级3级和4级)。视野变化情况为:5只眼(占8%)有轻度周边视野缩窄,19只眼(占26%)有周边视野缩窄伴弓形暗点,34只眼(占48%)视野缩窄至300度或更小,13只眼无法注视目标。术前眼压在21至30 mmHg之间的有12只眼(占17%),高于31 mmHg的有69只眼(占83%)。术后58只眼(占82%)眼压在10至15 mmHg之间,11只眼(占15%)眼压在16至20 mmHg之间。只有2只眼(占3%)眼压在20 mmHg稍低水平。
原发性开角型青光眼的特点是就诊较晚。在我们所在地区,小梁切除术联合应用5-氟尿嘧啶是首选的手术治疗方法,能有效控制眼压。有必要提高公众对青光眼的认识,以减少这类可避免的失明。