Kayange P C, Nkume H B, Feyi-Waboso A, Kalua K, Msukwa G, Schwering Schulze M
Ophthalmology Unit, Department of Surgery, College of Medicine, University of Malawi, Blantyre, Malawi; Lions Sight First Eye Hospital, Blantyre, Malawi.
Royal Gwent Hospital, Newport, Wales.
Malawi Med J. 2014 Sep;26(3):60-2.
Primary open angle glaucoma (POAG) is the most common type of glaucoma in Africa. We carried out a study to determine the clinical presentation pattern of patients with primary open angle glaucoma (POAG) at a tertiary hospital in Malawi.
A cross-sectional study.
Lions Sight First Eye Hospital-a major referral and teaching state eye hospital in Blantyre, Malawi.
Study participants were newly diagnosed POAG patients at specialist eye clinic during study period.
A total of 60 POAG patients were recruited into the study. The mean age was 58.7 years (SD= 16.6, range 18 - 86). There were more male (44, 73.3%) than female (16, 27.7%) patients. The majority of patients (73%) presented one year after onset of visual symptoms. Twenty-six patients (43%) had unilateral blindness (visual acuity < 3/60; WHO classification), while nine patients (15%) presented with bilateral blindness. A vertical cup-to-disc ratio (CDR) of 0.8 or worse was seen in 92 eyes (79%). The mean intraocular pressure (IOP) reading was 35.5 mmHg (SD 13.30). Of the thirty-three eyes that successfully underwent visual field analysis, very advanced defects were recorded in 12 eyes (36%).
This study demonstrates delayed presentation and male predominance among POAG patients at a tertiary eye hospital in Malawi. Glaucoma intervention programmes should aim at identifying patients with treatable glaucoma with particular attention to women.
原发性开角型青光眼(POAG)是非洲最常见的青光眼类型。我们开展了一项研究,以确定马拉维一家三级医院中原发性开角型青光眼(POAG)患者的临床表现模式。
横断面研究。
狮子会视觉第一眼科医院——马拉维布兰太尔一家主要的转诊和教学型国立眼科医院。
研究参与者为研究期间在专科眼科诊所新诊断的POAG患者。
共有60例POAG患者纳入研究。平均年龄为58.7岁(标准差=16.6,范围18 - 86岁)。男性患者(44例,73.3%)多于女性患者(16例,27.7%)。大多数患者(73%)在视觉症状出现一年后就诊。26例患者(43%)有单眼失明(视力<3/60;世界卫生组织分类),而9例患者(15%)为双眼失明。92只眼(79%)的垂直杯盘比(CDR)为0.8或更差。平均眼压(IOP)读数为35.5 mmHg(标准差13.30)。在成功进行视野分析的33只眼中,12只眼(36%)记录到非常严重的缺损。
本研究表明,在马拉维一家三级眼科医院的POAG患者中存在就诊延迟和男性占主导的情况。青光眼干预项目应旨在识别可治疗的青光眼患者,尤其要关注女性。