Yin Ting, Liu Hua, Wang Bin, Tu Guang-Zhong, Liang Hong, Zhao Yu-Ying
Department of Natural Medicines and the State Key Laboratory of Natural and Biomimetic Drug, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100083, China.
Yao Xue Xue Bao. 2008 Jan;43(1):67-70.
Spatholobus sinensis is a plant of the Spatholobus genus (Leguminosae family). Its caulis are used as "ji-xue-teng" regionally. However, to our knowledge, no phytochemical investigation on S. sinensis has been reported to date. In this study, eight compounds were isolated from the ethanol extract of the caulis of S. sinensis, by solvents extraction and column chromatography methods. By analysis of their physic-chemical constants and spectral data, the structures of 8 compounds were identified as spatholosineside A (1), 2',4',5,7-tetrahydroxyisoflavone (2), isoliquiritigenin (3), lupinalbin A (4), coumestrol (5), naringenin (6), protocatechuic acid (7), leonuriside A (8). Compound 1 is a new compound.
中华血藤是豆科血藤属的一种植物。在当地，其藤茎被用作“鸡血藤”。然而，据我们所知，迄今为止尚未有对中华血藤进行植物化学研究的报道。在本研究中，通过溶剂萃取和柱色谱法从中华血藤藤茎的乙醇提取物中分离出了8种化合物。通过对其理化常数和光谱数据的分析，鉴定出8种化合物的结构分别为血藤苷A（1）、2',4',5,7-四羟基异黄酮（2）、异甘草素（3）、羽扇豆醇A（4）、香豆雌酚（5）、柚皮素（6）、原儿茶酸（7）、益母草苷A（8）。化合物1是一种新化合物。
