Poeran J, Wildschut H, Gaytant M, Galama J, Steegers E, van der Meijden W
Erasmus MC, University Medical Centre Rotterdam, Department of Obstetrics & Gynaecology, CA Rotterdam, The Netherlands.
J Clin Virol. 2008 Aug;42(4):321-5. doi: 10.1016/j.jcv.2008.02.004. Epub 2008 Mar 21.
In The Netherlands the incidence of neonatal herpes was 2.0-2.9 per 100,000 live births during the period 1981-1998. The low incidence warranted a rather conservative prevention policy.
To monitor for potential changes in the incidence of neonatal herpes in The Netherlands between 1999 and 2005, which may affect the prevention policy.
Questionnaires were sent to all virological laboratories, the gynaecological and paediatric departments of every university hospital and half the number of the general hospitals in The Netherlands. The questionnaires pertained to the incidence of proven cases of neonatal herpes, the numbers of caesarean sections performed for the prevention of neonatal herpes and the numbers of pregnant women with genital herpes.
In the period 1999-2005 33 cases of neonatal herpes were reported, yielding an incidence of 3.2 cases per 100,000 live births per year. The estimated annual numbers of pregnant women with genital herpes ranged from 200 to 240. Approximately 9 caesarean sections were performed annually to prevent neonatal herpes.
In The Netherlands neonatal herpes is still a rare condition. From the findings of this study it is concluded that it is not necessary to revise the Dutch guidelines for the prevention of neonatal herpes simplex infection.
在荷兰，1981年至1998年期间新生儿疱疹的发病率为每10万例活产中有2.0 - 2.9例。低发病率使得预防政策较为保守。
监测1999年至2005年期间荷兰新生儿疱疹发病率的潜在变化，这些变化可能会影响预防政策。
向荷兰所有病毒学实验室、各大学医院的妇产科和儿科部门以及一半数量的综合医院发送了调查问卷。问卷涉及确诊的新生儿疱疹病例的发病率、为预防新生儿疱疹而进行的剖宫产数量以及患有生殖器疱疹的孕妇数量。
在1999年至2005年期间，报告了33例新生儿疱疹病例，每年每10万例活产中的发病率为3.2例。估计每年患有生殖器疱疹的孕妇数量在200至240人之间。每年约进行9次剖宫产以预防新生儿疱疹。
在荷兰，新生儿疱疹仍然是一种罕见疾病。从本研究的结果得出结论，没有必要修订荷兰预防新生儿单纯疱疹感染的指南。
