Xie Ming-Xing, Zhang Li, Lü Qing, Wang Xin-Fang, Han Wei, Zhang Jing, Liu Ying-Ying, Fu Qian, Xiang Fei-Xiang
Hubei Provincial Key Laboratory of Molecular Imaging, Department of Ultrasound, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2008 Feb;30(1):58-62.
To assess the left ventricular rotation and twist in patients with hypertrophic cardiomyopathy (HCM) by 2-dimensional ultrasound speckle-tracking imaging (STI).
Two-dimensional images of left ventricule (LV) at basal and apical short-axis views were acquired in 20 patients with HCM and 20 healthy subjects to evaluate LV rotation. LV twist were defined as rate of apical LV rotation to the basal. Peak rotation (Prot) and the time to Prot in basal and apical short axis views were measured separately. Peak twist (Ptw), twist at aortic valve closure (AVCtw), twist at mitral valve opening (MVOtw), untwisting rate (Untw R), and half time of untwisting (HTU) were calculated.
Compared with the control group, the value of Prot-MV, Prot-AP, Ptw, time to Ptw, AVCtw, MVOtw, and HTU significantly increased (all P < 0.05) and the Untw R significantly decreased (P < 0.05) in the HCM group. In the HCM group, time to Prot in apical view was significantly higher than that in basal view.
STI can noninvasively evaluate the characteristics of LV twist and rotation in patients with HCM.
通过二维超声斑点追踪成像（STI）评估肥厚型心肌病（HCM）患者的左心室旋转和扭转情况。
采集20例HCM患者和20例健康受试者左心室（LV）基底和心尖短轴视图的二维图像，以评估LV旋转。LV扭转定义为心尖LV旋转与基底旋转的比率。分别测量基底和心尖短轴视图中的峰值旋转（Prot）和达到Prot的时间。计算峰值扭转（Ptw）、主动脉瓣关闭时的扭转（AVCtw）、二尖瓣开放时的扭转（MVOtw）、解旋速率（Untw R）和解旋半衰期（HTU）。
与对照组相比，HCM组中Prot-MV、Prot-AP、Ptw、达到Ptw的时间、AVCtw、MVOtw和HTU的值显著增加（均P < 0.05），而Untw R显著降低（P < 0.05）。在HCM组中，心尖视图中达到Prot的时间显著高于基底视图。
STI可无创评估HCM患者LV扭转和旋转的特征。
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