Krasnow S H
Oncology Section, Washington VA Medical Center.
Oncology (Williston Park). 1991 Sep;5(9 Suppl):19-24.
The author reviews the physiology of the various types of emesis and the factors that influence chemotherapy-induced nausea and vomiting, including both patient-related factors and those related to treatment. He then enumerates and describes the antiemetic agents now available, ranging from phenothiazines to cannabinoids and serotonin (5-hydroxytryptamine) antagonists; explains how they might best be used; and outlines the probable future direction for antiemetic studies.
作者回顾了各类呕吐的生理学机制以及影响化疗引起的恶心和呕吐的因素，包括与患者相关的因素和与治疗相关的因素。然后，他列举并描述了目前可用的止吐药，从吩噻嗪类到大麻素类以及5-羟色胺拮抗剂；解释了如何能最好地使用这些药物；并概述了止吐研究可能的未来方向。
