Wilks C R, Studdert M J
Aust Vet J. 1976 May;52(5):199-203. doi: 10.1111/j.1751-0813.1976.tb00064.x.
The immunological and virological status of 3 foals in respect of equine herpesviruses (EHV) was established and the foals were sequentially infected with EHV2, EHV3 and EHV1. Following experimental infection with EHV2, no clinical signs of disease were observed in any foal. The inoculation of EHV3 into the genital tract resulted in lesions of the mucous membrane and perineal skin that were considered typical of equine coital exanthema. Following intransal inoculation of EHV3 extensive ulceration and pustule formation on the nasal mucosa was observed by day 5 accompanied at day 7 by a profuse, mucopurulent nasal discharge; on day 8 pustular lesions of the skin about the external nares appeared. Signs of disease after inoculation with EHV1 were milder than expected in 2 of the 3 foals. The possibility that recent, prior infection with EHV2 and/or 3 may protect against EHV1 was considered.
确定了3匹小马驹在马疱疹病毒（EHV）方面的免疫和病毒学状况，并依次用EHV2、EHV3和EHV1感染这些小马驹。在用EHV2进行实验性感染后，任何一匹小马驹均未观察到疾病的临床症状。将EHV3接种到生殖道导致黏膜和会阴皮肤出现病变，这些病变被认为是马交媾疹的典型症状。在用EHV3经鼻接种后，到第5天观察到鼻黏膜出现广泛溃疡和脓疱形成，第7天伴有大量黏液脓性鼻分泌物；第8天，外鼻孔周围皮肤出现脓疱性病变。在接种EHV1后，3匹小马驹中有2匹的疾病症状比预期的要轻。研究了近期先前感染EHV2和/或3可能对EHV1有保护作用的可能性。
