Gleeson L J, Sullivan N D, Studdert M J
Aust Vet J. 1976 Aug;52(8):349-54. doi: 10.1111/j.1751-0813.1976.tb09485.x.
The inoculation of equine herpesvirus type 3 (EHV3) strain 65/61 into the amniotic cavity of a mare 6-7 months pregnant resulted in abortion 11 days later. Following abortion typical lesions of coital exanthema were not observed in the genital tract of the mare, nor was EHV3 isolated from her. Serological evidence, however, indicated that the mare was infected with EHV3 following inoculation. Grossly the foetal disease was characterised by placentitis, focal ulcerative dermatitis, focal necrosis of the lungs and a striking diptheritic gastritis. Histological findings were interstitial pneumonia, diffuse hepatitis, generalised myositis, extensive vascular necrosis and degeneration of a range of epithelial cells. EHV3 was isolated from the placenta and placental fluids, stomach fluid, pooled thoracic and abdominal fluid, skin, lung, spleen and small intestine of the foetus.
将马疱疹病毒3型（EHV3）毒株65/61接种到一匹怀孕6至7个月母马的羊膜腔中，11天后导致母马流产。流产后，在母马生殖道中未观察到典型的交媾疹病变，也未从其体内分离出EHV3。然而，血清学证据表明，接种后该母马感染了EHV3。大体上，胎儿疾病的特征为胎盘炎、局灶性溃疡性皮炎、肺部局灶性坏死和显著的白喉性胃炎。组织学检查结果为间质性肺炎、弥漫性肝炎、全身性肌炎、广泛的血管坏死以及一系列上皮细胞的变性。从胎儿的胎盘和羊水、胃液、胸腔和腹腔积液、皮肤、肺、脾和小肠中分离出了EHV3。
