Boscia Francesco, Furino Claudio, Recchimurzo Nicola, Besozzi Gianluca, Sborgia Giancarlo, Sborgia Carlo
Dipartimento di Oftalmologia ed Otorinolaringoiatria, Università di Bari, Piazza Giulio Cesare, 11-70124 Bari, Italy.
Graefes Arch Clin Exp Ophthalmol. 2008 Jul;246(7):943-8. doi: 10.1007/s00417-008-0806-7. Epub 2008 Mar 28.
To compare pars plana vitrectomy (PPV) with 1300 cs silicone oil and scleral buckle (SB) vs PPV with Oxane HD tamponade for rhegmatogenous retinal detachment (RRD) with inferior retinal breaks (IRB).
Twenty eyes of 20 consecutive patients with primary inferior RRD and PVR >or=CP2 were alternatively assigned to PPV and 1300 cs silicone oil and segmental SB in the inferior periphery (group 1, n = 10) or PPV with Oxane HD (group 2, n = 10) in order of presentation. Silicone oil/Oxane HD removal was performed 12 weeks after surgery. Subjects were followed up for 6 months from oil removal.
Operative time was lower in Oxane HD group (P = 0.012). In both groups, the retina was primary reattached at the third month after oil removal in nine eyes (90%). At the end of follow-up, retina was reattached in nine eyes (90%) in group 1 (including one eye with oil in situ), and in eight eyes (80%) in group 2 (P > 0.05).
Silicone oil+SB and Oxane HD appear equal for primary RRD with IRB, but a large multi-centre study is required. Oxane HD permitted a reduced operative time.
比较玻璃体切除术（PPV）联合1300厘沲硅油和巩膜扣带术（SB）与PPV联合Oxane HD眼内填充治疗伴有下方视网膜裂孔（IRB）的孔源性视网膜脱离（RRD）的效果。
连续纳入20例患有原发性下方RRD且增殖性玻璃体视网膜病变（PVR）≥CP2的患者，共20只眼，按照就诊顺序交替分配至PPV联合1300厘沲硅油和下方周边部节段性SB组（第1组，n = 10）或PPV联合Oxane HD组（第2组，n = 10）。术后12周取出硅油/Oxane HD。自取出填充物后对受试者进行6个月的随访。
Oxane HD组的手术时间较短（P = 0.012）。两组中，9只眼（90%）在取出填充物后的第三个月视网膜实现了初次复位。随访结束时，第1组9只眼（90%）视网膜复位（包括1只眼硅油原位留存），第2组8只眼（80%）视网膜复位（P > 0.05）。
对于伴有IRB的原发性RRD，硅油+SB和Oxane HD似乎效果相当，但需要开展大规模多中心研究。Oxane HD可缩短手术时间。
