微流控设备上的实际样本分析。

Real sample analysis on microfluidic devices.

作者信息

Crevillén Agustin González, Hervás Miriam, López Miguel Angel, González Maria Cristina, Escarpa Alberto

机构信息

Department of Analytical Chemistry and Chemical Engineering, University of Alcala, E-28871 Alcala de Henares, Madrid, Spain.

出版信息

Talanta. 2007 Dec 15;74(3):342-57. doi: 10.1016/j.talanta.2007.10.019. Epub 2007 Oct 18.

DOI:10.1016/j.talanta.2007.10.019

PMID:18371648

Abstract

This review covers the state of the art of the analysis of real (or non-ideal) samples on microfluidic devices. A real sample analysis performed on microfluidics conceptually involves the complete integration of sample preparation, analyte separation, and detection on these platforms. Different "lab-on-a-chip" approaches have emerged in relevant application areas such as clinical, environmental, and food analysis which will be critically illustrated and discussed with respect to the strengths and weakness found. Likewise, the main challenges and perspectives will also be commented on.

摘要

本综述涵盖了微流控装置上实际（或非理想）样品分析的最新技术。在微流控上进行的实际样品分析在概念上涉及这些平台上样品制备、分析物分离和检测的完全集成。在临床、环境和食品分析等相关应用领域已经出现了不同的“芯片实验室”方法，将根据发现的优缺点进行批判性说明和讨论。同样，也将对主要挑战和前景进行评论。