Faro G, Jarre P, Martucci M, Sargiotto A, Eandi M
Centro Tossicodipendenze, USSL VI Torino.
Clin Ter. 1991;139(3-4):93-9.
Naltrexone is a pure narcotic antagonist with optimum pharmacologic properties for the long-term management of opiate addiction. The above study confirms the usefulness of naltrexone for the prevention of relapse in subjects who have been weaned from narcotics. However, the short follow up does not yet permit evaluation of its medium and long-term efficacy. The better course and outcome of treatment are significantly related to certain characteristics and types of addicts. It may be said that by assuring complete, albeit time-limited, remission the antagonist allows the addict to open a window through which to face the world, and offers the therapist the possibility to apply all the instruments at his disposal in an effective manner.
纳曲酮是一种纯阿片类拮抗剂，具有用于阿片类成瘾长期管理的最佳药理学特性。上述研究证实了纳曲酮在预防已停用麻醉药品的受试者复发方面的有效性。然而，短期随访尚无法评估其中长期疗效。治疗的更好过程和结果与某些成瘾者的特征和类型显著相关。可以说，通过确保完全缓解（尽管是有限时间的），拮抗剂使成瘾者能够打开一扇面对世界的窗口，并为治疗师提供了有效运用其所有可用手段的可能性。
