Rodríguez-Marco N A, Andonegui-Navarro J, Compains-Silva E, Rebollo-Aguayo A, Aliseda-Pérez-de-Madrid D, Aranguren-Laflin M
Servicio de Oftalmología, Hospital de Navarra, Pamplona, España.
Arch Soc Esp Oftalmol. 2008 Apr;83(4):267-71. doi: 10.4321/s0365-66912008000400010.
Ocular examinations and optical coherence tomography (OCT) were performed in three patients with retinal phototoxicity lesions. Fluorescein angiography depicted a window defect. OCT exhibited hyporeflectivity at the outer foveal retina and fragmentation of the inner reflective layers, corresponding to the junction between the inner and outer photoreceptor segments.
Retinal damage after light exposure has a rapid onset and shows different patterns in OCT examination. OCT findings suggest that decreased visual acuity may be associated with full-thickness photoreceptors and retinal pigment epithelium (RPE) involvement. OCT is a useful tool for objective assessment of retinal pathology in phototoxicity cases where fundus changes may be minimal or absent.
对三名患有视网膜光毒性损伤的患者进行了眼部检查和光学相干断层扫描（OCT）。荧光素血管造影显示有窗样缺损。OCT显示在中央凹外视网膜处反射性降低，内反射层破碎，对应于内、外光感受器节段之间的交界处。
光照后视网膜损伤起病迅速，在OCT检查中表现出不同的模式。OCT检查结果表明，视力下降可能与全层光感受器和视网膜色素上皮（RPE）受累有关。在眼底变化可能很轻微或不存在的光毒性病例中，OCT是客观评估视网膜病变的有用工具。
