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[留尼汪岛地方性甲状腺肿的发病率。病因学因素研究]

[Incidence of endemic goiter on Reunion Island. A search for etiological factors].

作者信息

Jaffiol C, Manderscheid J C, Gatina J H, Baldet L, Percheron C

机构信息

Département de l'Information médicale, Hôpital Lapeyronie, Montpellier.

出版信息

Presse Med. 1991 Dec 7;20(42):2139-43.

PMID:1837362
Abstract

In an epidemiological study carried out in Reunion Island, 1,686 randomized school children aged from 11 to 15 years were examined for goitre by cervical palpation. A detailed questionnaire was fully completed by each child and his parents. The iodine level was measured in 168 urinary samples and in the salt and water consumed in the various places investigated. The overall incidence of goitre was 8.2 percent, rising up to 19.7 percent in the mountainous part of the island. The mean urinary iodine level was 40.2 +/- 2.7 micrograms I/g creatinine (m +/- SEM) and fell to 20.0 +/- 3.7 in the highlands. Water and salt contained little iodine. A significant relationship was noted between the presence of goitre on the one hand and sex, familial incidence of goitre, cassava consumption and distance from the coast on the other hand. This study demonstrates that endemic goitre and iodine deficiency are present in a limited area of Reunion Island.

摘要

在留尼汪岛进行的一项流行病学研究中,对1686名年龄在11至15岁之间的随机抽取的在校儿童进行了颈部触诊检查甲状腺肿。每个孩子及其父母都完整填写了一份详细问卷。对168份尿样以及在各个调查地点所消耗的盐和水中的碘含量进行了测量。甲状腺肿的总体发病率为8.2%,在该岛山区升至19.7%。尿碘平均水平为40.2±2.7微克碘/克肌酐(平均值±标准误),在高地降至20.0±3.7。水和盐中的碘含量很少。一方面甲状腺肿的存在与性别、甲状腺肿的家族发病率、木薯食用量以及与海岸的距离之间存在显著关系。这项研究表明,留尼汪岛的一个有限区域存在地方性甲状腺肿和碘缺乏情况。

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