Eltom M, Hofvander Y, Torelm I, Fellström B
Acta Med Scand. 1984;215(5):467-75. doi: 10.1111/j.0954-6820.1984.tb17680.x.
In the Darfur region of Sudan, 85.5% of 7134 subjects examined, mainly school children, had goitre and in 23.9% the goitre was large (stage II or III). The prevalence of goitre was high in prepubertal children of both sexes and in adult females. There was a higher frequency of large goitre in the rural than in the urban areas (40.9 and 11.4%, respectively). In Port Sudan on the Red Sea Coast the goitre rate was 13.5% among 7697 schoolchildren, but here visible goitre was extremely rare. Of the subjects from Darfur, 54.5% excreted less than 50 micrograms of iodine/g creatinine, while all except one subject in Port Sudan excreted more than that. The median urinary excretion of iodine was 45.3 micrograms/g in subjects from Darfur and 171.2 in those from Port Sudan, the mean value being significantly lower in the former than in the latter (p less than 0.001). The iodine content of all water samples was very low, and the contents of calcium and fluoride were not high. Other goitrogenic factors could not be excluded. However, iodine deficiency is the major cause of goitre in the Darfur region and a prophylactic programme is urgently needed.
在苏丹的达尔富尔地区，接受检查的7134名对象（主要是学童）中有85.5%患有甲状腺肿，其中23.9%的甲状腺肿为大型（II期或III期）。青春期前男女儿童及成年女性的甲状腺肿患病率都很高。农村地区大型甲状腺肿的发生率高于城市地区（分别为40.9%和11.4%）。在红海沿岸的苏丹港，7697名学童中的甲状腺肿发生率为13.5%，但此处可见的甲状腺肿极为罕见。来自达尔富尔的对象中，54.5%的人每克肌酐碘排泄量低于50微克，而苏丹港除一名对象外的所有人排泄量均高于此值。达尔富尔地区对象的尿碘排泄中位数为45.3微克/克，苏丹港对象的为171.2微克/克，前者的平均值显著低于后者（p<0.001）。所有水样的碘含量都很低，钙和氟的含量也不高。不能排除其他致甲状腺肿因素。然而，碘缺乏是达尔富尔地区甲状腺肿的主要原因，迫切需要开展预防计划。
