Lee Myeong Soo, Lam Paul, Ernst Edzard
Complementary Medicine, Peninsula Medical School, Universities of Exeter & Plymouth, 25 Victoria Park Road, Exeter, Devon EX2 4NT, UK.
Parkinsonism Relat Disord. 2008 Dec;14(8):589-94. doi: 10.1016/j.parkreldis.2008.02.003. Epub 2008 Apr 18.
The objective of this review is to assess the effectiveness of tai chi as a treatment option for Parkinson's disease (PD). We have searched the literature using 21 databases from their inceptions to January 2008, without language restrictions. We included all types of clinical studies regardless of their design. Their methodological quality was assessed using the modified Jadad score. Of the seven studies included, one randomised clinical trial (RCT) found tai chi to be superior to conventional exercise in terms of the Unified PD Rating Scale (UPDRS) and prevention of falls. Another RCT found no effects of tai chi on locomotor ability compared with qigong. The third RCT failed to show effects of tai chi on the UPDRS and the PD Questionnaires compared with wait list control. The remaining studies were either non-randomised (n=1) or uncontrolled clinical trials (n=3). Collectively these data show that RCTs of the tai chi for PD are feasible but scarce. Most investigations suffer from methodological flaws such as inadequate study design, poor reporting of results, small sample size, and publication without appropriate peer review process. In conclusion, the evidence is insufficient to suggest tai chi is an effective intervention for PD. Further research is required to investigate whether there are specific benefits of tai chi for people with PD, such as its potential effect on balance and on the frequency of falls.
本综述的目的是评估太极拳作为帕金森病(PD)治疗选择的有效性。我们检索了21个数据库,从其创建至2008年1月,无语言限制。我们纳入了所有类型的临床研究,无论其设计如何。使用改良的Jadad评分评估其方法学质量。在纳入的七项研究中,一项随机临床试验(RCT)发现,在统一帕金森病评定量表(UPDRS)和预防跌倒方面,太极拳优于传统运动。另一项RCT发现,与气功相比,太极拳对运动能力没有影响。第三项RCT未能显示与等待名单对照相比,太极拳对UPDRS和帕金森病问卷有影响。其余研究要么是非随机的(n = 1),要么是无对照的临床试验(n = 3)。总体而言,这些数据表明,针对PD的太极拳RCT是可行的,但数量稀少。大多数研究存在方法学缺陷,如研究设计不充分、结果报告不佳、样本量小以及未经适当同行评审程序就发表。总之,证据不足表明太极拳是一种有效的PD干预措施。需要进一步研究以调查太极拳对PD患者是否有特定益处,例如其对平衡和跌倒频率的潜在影响。