在急性抗阻运动期间，瘦男性和肥胖男性的脂肪组织脂肪分解均上调。
Adipose tissue lipolysis is upregulated in lean and obese men during acute resistance exercise.
作者信息
Chatzinikolaou Athanasios, Fatouros Ioannis, Petridou Anatoli, Jamurtas Athanasios, Avloniti Alexandra, Douroudos Ioannis, Mastorakos George, Lazaropoulou Christina, Papassotiriou Ioannis, Tournis Symeon, Mitrakou Asimina, Mougios Vassilis
机构信息
Department of Physical Education and Sports Science, University of Thrace, Komotini, Greece.
出版信息
Diabetes Care. 2008 Jul;31(7):1397-9. doi: 10.2337/dc08-0072. Epub 2008 Mar 28.
OBJECTIVE
To investigate the effect of acute resistance exercise on adipose tissue triacylglycerol lipase activity (TGLA) in lean and obese men.
RESEARCH DESIGN AND METHODS
Nine lean and eight obese men performed 30 min of circuit resistance exercise. Adipose tissue and blood were sampled during exercise for TGLA, metabolite, and hormone determinations. Respiratory exchange ratio (RER) was measured throughout exercise.
RESULTS
Energy expenditure of exercise relative to body mass was higher in the lean and RER was higher in the obese men, suggesting lower fat oxidation. TGLA increased 18-fold at 5 min of exercise in the lean men and 16-fold at 10 min of exercise in the obese men. The delayed lipolytic activation in the obese men was reflected in serum nonesterified fatty acid and glycerol concentrations. Plasma insulin increased in the obese but did not change in the lean men.
CONCLUSIONS
Resistance exercise upregulated adipose tissue lipolysis and enhanced energy expenditure in lean and obese men, with a delayed lipolytic activation in the obese men.
目的
研究急性抗阻运动对瘦体重男性和肥胖男性脂肪组织甘油三酯脂肪酶活性（TGLA）的影响。
研究设计与方法
9名瘦体重男性和8名肥胖男性进行了30分钟的循环抗阻运动。在运动期间采集脂肪组织和血液样本，用于测定TGLA、代谢物和激素。在整个运动过程中测量呼吸交换率（RER）。
结果
相对于体重，瘦体重男性运动的能量消耗更高，而肥胖男性的RER更高，这表明脂肪氧化较低。瘦体重男性在运动5分钟时TGLA增加了18倍，肥胖男性在运动10分钟时TGLA增加了16倍。肥胖男性脂肪分解激活延迟反映在血清非酯化脂肪酸和甘油浓度上。肥胖男性血浆胰岛素升高，而瘦体重男性则无变化。
结论
抗阻运动上调了瘦体重男性和肥胖男性的脂肪组织脂肪分解并增加了能量消耗，肥胖男性的脂肪分解激活延迟。
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