Armster H, Schwarz T
Dermatologische Abteilung, Krankenhaus der Stadt Wien-Lainz.
Hautarzt. 1991 Nov;42(11):713-6.
Noninfectious pustular reactions can be observed in association with a variety of dermatoses. Thus, precise knowledge of these is important for the differential diagnosis. Toxic pustuloderma (TP) has been described as a clinical entity and is characterenized by the sudden onset of intense erythemas followed by sterile pustulation, primarily located in the flexural areas and groins. Most frequently TP is induced by drugs, in particular by betalactam antibiotics. In this paper, a typical case of TP caused by the combination of amoxicillin and clavulanic acid will be described, and clinical features, pathogenesis and differential diagnosis will be discussed.
非感染性脓疱反应可见于多种皮肤病。因此，准确了解这些反应对于鉴别诊断很重要。毒性脓疱性皮炎（TP）已被描述为一种临床实体，其特征为突然出现强烈红斑，随后出现无菌性脓疱，主要位于屈侧部位和腹股沟。TP最常见由药物引起，尤其是β-内酰胺类抗生素。本文将描述一例由阿莫西林和克拉维酸联合使用引起的TP典型病例，并讨论其临床特征、发病机制和鉴别诊断。
