Ferguson J E, Chalmers R J
University Department of Dermatology, Salford Royal Hospitals NHS Trust, Lancs, UK.
Clin Exp Dermatol. 1996 Jan;21(1):54-5.
Enalapril is widely prescribed for hypertension and cardiac failure. Rashes are an uncommon side-effect, occurring in approximately 1.4% of patients, and in approximately 0.4% of patients the rash is sufficient to require discontinuation of enalapril. (Merck Sharp and Dohme, pers. comm.) We report a case of toxic pustuloderma related to enalapril therapy for congestive cardiac failure. To our knowledge enalapril-induced toxic pustuloderma has not been previously reported.
依那普利被广泛用于治疗高血压和心力衰竭。皮疹是一种不常见的副作用，约1.4%的患者会出现，约0.4%的患者皮疹严重到需要停用依那普利。（默克夏普与多贺美公司，个人交流）我们报告一例与依那普利治疗充血性心力衰竭相关的中毒性脓疱病病例。据我们所知，依那普利诱发的中毒性脓疱病此前尚未见报道。
