氧氟沙星诱发的中毒性脓疱病。
Toxic pustuloderma induced by ofloxacin.
作者信息
Tsuda S, Kato K, Karashima T, Inou Y, Sasai Y
机构信息
Department of Dermatology, Kurume University School of Medicine, Japan.
出版信息
Acta Derm Venereol. 1993 Oct;73(5):382-4. doi: 10.2340/0001555573382384.
A patient with drug-induced toxic pustuloderma is presented. The patient, who was asthmatic and who was being treated with ofloxacin for bronchitis and pharyngitis, developed intense erythemas followed by subcorneal pustulation associated with fever and a neutrophil leukocytosis. The diagnosis was confirmed by oral readministration of ofloxacin, with the result that pustular eruptions were induced. This form of drug eruption had not previously been attributed to ofloxacin.
本文报告1例药物性中毒性脓疱病患者。该患者患有哮喘，因支气管炎和咽炎正在接受氧氟沙星治疗，出现了严重红斑，随后出现角膜下脓疱，并伴有发热和中性粒细胞增多。通过再次口服氧氟沙星诱发脓疱性皮疹，确诊了该诊断。这种药疹形式以前未曾归因于氧氟沙星。
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