Sumimoto T, Hamada M, Muneta S, Shigematsu Y, Fujiwara Y, Sekiya M, Kazatani Y, Hiwada K
Second Department of Internal Medicine, Ehime University School of Medicine, Japan.
J Hum Hypertens. 1991 Oct;5(5):399-403.
The influence of age and severity of hypertension on the blood pressure response to isometric handgrip exercise (IHG) was studied in essential hypertensive patients (n = 122). The change in blood pressure during IHG in elderly patients with isolated systolic hypertension (ISH) (n = 12) was also studied. Left ventricular hypertrophy due to hypertension was used as an index of the severity of hypertension. The change in systolic blood pressure (SBP) during IHG was markedly greater in essential hypertensives than in normotensive subjects (n = 36). Among hypertensive patients, the change in SBP increased with increasing severity of hypertension. This change in SBP was not influenced by age. The change in SBP during IHG in patients with ISH was significantly smaller than that in essential hypertensive patients and was similar to that in normotensive subjects in the elderly. These results demonstrate that age does not affect the increased blood pressure response to IHG in essential hypertensive patients but the greater the severity of hypertension, the greater the increase in SBP during IHG. Elderly patients with ISH do not have an enhanced blood pressure response to IHG.
在122例原发性高血压患者中研究了年龄和高血压严重程度对等长握力运动（IHG）血压反应的影响。还研究了12例老年单纯收缩期高血压（ISH）患者在IHG期间的血压变化。将高血压所致的左心室肥厚用作高血压严重程度的指标。原发性高血压患者在IHG期间收缩压（SBP）的变化明显大于血压正常者（36例）。在高血压患者中，SBP的变化随高血压严重程度的增加而增加。SBP的这种变化不受年龄影响。ISH患者在IHG期间SBP的变化明显小于原发性高血压患者，且与老年血压正常者相似。这些结果表明，年龄不影响原发性高血压患者对IHG血压升高的反应，但高血压严重程度越高，IHG期间SBP升高幅度越大。老年ISH患者对IHG没有增强的血压反应。
