一种尿觉实时尿动力学测量方法的验证

Validation of a real-time urodynamic measure of urinary sensation.

作者信息

Lowenstein Lior, FitzGerald Mary P, Kenton Kimberly, Brubaker Linda, Gruenwald Ilan, Papier Irena, Durazo-Arvizu Ramón A, Elliot Christina, Mueller Elizabeth R, Vardi Yoram

机构信息

Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Loyola Medical Center, Chicago, IL 60153, USA.

出版信息

Am J Obstet Gynecol. 2008 Jun;198(6):661.e1-4; discussion 661.e4-5. doi: 10.1016/j.ajog.2008.02.023. Epub 2008 Apr 2.

DOI:10.1016/j.ajog.2008.02.023

PMID:18377858

Abstract

OBJECTIVE

The purpose of this study was to test the feasibility and validity of a continuous measurement of urinary sensation during cystometry.

STUDY DESIGN

Subjects continuously recorded their level of urinary sensation during cystometry with the use of urodynamic diagnoses and responses to the Medical Epidemiologic and Social Aspects of Aging (MESA) and Urinary Distress Inventory (UDI) scales. Trends in urinary sensation recordings by increasing percentage of maximum cystometric capacity (MCC) were captured and compared with the use of growth curves.

RESULTS

Fifty-one women participated: 18 patients had detrusor overactivity incontinence (DOI); 15 patients had urodynamic stress incontinence; 9 patients had mixed incontinence, and 9 patients did not demonstrate incontinence. In the volume range between 35% and 75% of MCC, the mean sensation level was higher in the DOI group than the other groups (P < .04). Urge sensation at 50% of MCC correlated with UDI and MESA urge subscales (rho = 0.34, p < .03 and rho = 0.39, p < .02).

CONCLUSION

This study demonstrates that the Urgeometer measurement is feasible and correlates with urodynamic diagnosis and the severity and bother from urge incontinence.

摘要

目的

本研究旨在测试膀胱测压期间连续测量尿意的可行性和有效性。

研究设计

受试者在膀胱测压期间使用尿动力学诊断以及对衰老的医学流行病学和社会方面（MESA）量表及尿路困扰量表（UDI）的反应，连续记录其尿意水平。通过增加最大膀胱测压容量（MCC）的百分比来捕捉尿意记录的趋势，并与生长曲线的使用进行比较。

结果

51名女性参与研究：18例患者为逼尿肌过度活动型尿失禁（DOI）；15例患者为尿动力学压力性尿失禁；9例患者为混合性尿失禁，9例患者未表现出尿失禁。在MCC的35%至75%的容量范围内，DOI组的平均感觉水平高于其他组（P < .04）。MCC达到50%时的尿急感觉与UDI及MESA尿急子量表相关（rho = 0.34，p < .03；rho = 0.39，p < .02）。