Duggan Paul
Discipline of Obstetrics and Gynaecology, The University of Adelaide, South Australia, Australia.
Aust N Z J Obstet Gynaecol. 2011 Oct;51(5):416-20. doi: 10.1111/j.1479-828X.2011.01344.x. Epub 2011 Aug 2.
Several population-based and clinical studies report that stress incontinence has less impact on quality of life (QoL) than urge incontinence and overactive bladder.
This research aimed to determine if this relationship held true for urodynamic diagnoses.
Quality of life was evaluated by the King's Health Questionnaire prior to urodynamic testing in 326 women presenting with lower urinary tract symptoms and who completed a 48-h frequency volume chart. Urodynamic results were categorised as 'normal', 'sensory abnormalities only', 'idiopathic detrusor overactivity (IDO) only', 'urodynamic stress incontinence (USI) only' or 'mixed (IDO and USI)'. QoL data were compared using these diagnostic categories.
Women in mixed, USI and IDO categories had significantly worse QoL scores in the domain Severity Measures than women in sensory or normal categories (P < 0.0001). Incontinence Impact was significantly worse in mixed and IDO categories compared with normal (P = 0.006) but not compared with women with USI. Sleep/Energy scores were significantly worse for women in mixed and IDO categories compared with women with USI (P = 0.003). Significant differences between urodynamic categories were also observed in the domains Role Limitations, Social Limitations and General Health.
Mixed incontinence had the greatest adverse effect on QoL; however, any abnormal urodynamic diagnosis was associated with a significantly adverse effect. Although a normal urodynamic result was associated with less impact on QoL than an abnormal result, there was still an effect present. The optimal management (eg conservative vs surgical management) of women with a normal urodynamic result is yet to be established.
多项基于人群的研究和临床研究报告称,压力性尿失禁对生活质量(QoL)的影响小于急迫性尿失禁和膀胱过度活动症。
本研究旨在确定这种关系在尿动力学诊断中是否成立。
在对326名出现下尿路症状并完成48小时频率容量图表的女性进行尿动力学检查之前,通过国王健康问卷评估生活质量。尿动力学结果分为“正常”、“仅感觉异常”、“仅特发性逼尿肌过度活动(IDO)”、“仅尿动力学压力性尿失禁(USI)”或“混合性(IDO和USI)”。使用这些诊断类别比较生活质量数据。
混合性、USI和IDO类别的女性在严重程度测量领域的生活质量得分明显低于感觉或正常类别的女性(P < 0.0001)。与正常类别相比,混合性和IDO类别的失禁影响明显更差(P = 0.006),但与USI女性相比则不然。与USI女性相比,混合性和IDO类别的女性睡眠/能量得分明显更差(P = 0.003)。在角色限制、社会限制和总体健康领域也观察到尿动力学类别之间的显著差异。
混合性尿失禁对生活质量的不良影响最大;然而,任何异常的尿动力学诊断都与明显的不良影响相关。尽管正常的尿动力学结果对生活质量的影响比异常结果小,但仍然存在影响。尿动力学结果正常的女性的最佳管理方法(例如保守治疗与手术治疗)尚未确定。