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女性对含益生菌大豆提取物功效的认知:M3研究

Women's perception of the efficacy of a soy extract with probiotic: the M3 study.

作者信息

Palacios Santiago, Rojo Ignacio Alvarez, Cancelo Maria Jesús, Neyro José Luis, Castelo-Branco Camil

机构信息

Instituto Palacios de Salud y, Medicina de la Mujer, Madrid, Spain.

出版信息

Gynecol Endocrinol. 2008 Apr;24(4):178-83. doi: 10.1080/09513590801954687.

DOI:10.1080/09513590801954687
PMID:18382902
Abstract

OBJECTIVES

To determine women's perception of soy extracts containing a probiotic on climacteric-related symptoms.

DESIGN

A prospective multi-center survey.

SUBJECTS AND METHODS

A total of 2044 women aged 40-65 years, who were recruited at random by a group of 198 Spanish gynecologists. The women completed a self-report survey at baseline and after 6 months' use of the soy extract (30 mg genistein and 30 mg daidzein) with probiotic (500 million spores of Lactobacillus sporogenes), calcium (141 mg) and vitamin D (5 microg). The questionnaire included 15 items on menopause and health and four about sexuality from the Cervantes scale. Patients and gynecologists completed an assessment about the clinical state.

RESULTS

After 6 months, the studied soy extract improved climacteric symptoms and sexuality. Both patients and gynecologists were satisfied with the results.

CONCLUSION

Peri- and postmenopausal patients usually experience common menopausal symptoms and many believe that soy extract improves their menopause symptoms. Physicians should be aware of patients' positive attitude to such products.

摘要

目的

确定女性对含有益生菌的大豆提取物对更年期相关症状的看法。

设计

一项前瞻性多中心调查。

研究对象与方法

由198名西班牙妇科医生随机招募了2044名年龄在40至65岁之间的女性。这些女性在基线时以及使用含有益生菌(5亿孢子的产孢乳酸杆菌)、钙(141毫克)和维生素D(5微克)的大豆提取物(30毫克染料木黄酮和30毫克大豆苷元)6个月后完成了一份自我报告调查。问卷包括15项关于更年期与健康的内容以及4项来自塞万提斯量表的关于性方面的内容。患者和妇科医生完成了关于临床状况的评估。

结果

6个月后,所研究的大豆提取物改善了更年期症状和性功能。患者和妇科医生对结果都很满意。

结论

围绝经期和绝经后患者通常会经历常见的更年期症状,许多人认为大豆提取物能改善她们的更年期症状。医生应该意识到患者对这类产品的积极态度。

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