戈登氏链球菌中葡糖基转移酶相变的生态学意义
Ecological implications of glucosyltransferase phase variation in Streptococcus gordonii.
作者信息
Vickerman M M, Clewell D B, Jones G W
机构信息
Department of Cariology and General Dentistry, School of Dentistry, Unviersity of Michigan, Ann Arbor 48109-0620.
出版信息
Appl Environ Microbiol. 1991 Dec;57(12):3648-51. doi: 10.1128/aem.57.12.3648-3651.1991.
Abstract
When sucrose is provided as a substrate for glucosyltransferase (GTF), Spp+ cells of the oral bacteria Streptococcus gordonii grow embedded in an insoluble glucan mass associated with surfaces. Spp- phase variants with lower GTF activity, which either arise from or are grown with Spp+ cells, segregate preferentially as unattached cells in the culture supernatants. Conversely, Spp+ revertants preferentially accumulate on surfaces. GTF phase variation, therefore, may facilitate the dispersion of S. gordonii cells throughout the oral cavity.
摘要
当蔗糖作为葡糖基转移酶（GTF）的底物时，口腔细菌戈登链球菌的Spp +细胞生长在与表面相关的不溶性葡聚糖团块中。具有较低GTF活性的Spp-相变体，其要么由Spp +细胞产生，要么与Spp +细胞一起生长，它们优先作为未附着的细胞分离到培养上清液中。相反，Spp +回复体优先在表面聚集。因此，GTF相变异可能有助于戈登链球菌细胞在整个口腔中的扩散。
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