Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes.
作者信息
Pelka Peter, Ablack Jailal N G, Fonseca Gregory J, Yousef Ahmed F, Mymryk Joe S
机构信息
Department of Microbiology and Immunology, The University of Western Ontario, London Regional Cancer Program, London, Ontario, Canada N6A 4L6.
出版信息
J Virol. 2008 Aug;82(15):7252-63. doi: 10.1128/JVI.00104-08. Epub 2008 Apr 2.
Abstract
摘要
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本文引用的文献
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Adenovirus e1a proteins and transformation (review).腺病毒 E1A 蛋白与转化（综述）。
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Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor.与腺病毒E1A结合的视网膜母细胞瘤蛋白结构揭示了病毒癌蛋白使肿瘤抑制因子失活的分子基础。
Genes Dev. 2007 Nov 1;21(21):2711-6. doi: 10.1101/gad.1590607.
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Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition.组蛋白基因的转录激活需要在G1/S期转换过程中，NPAT依赖的TRRAP-Tip60复合物募集到组蛋白启动子区域。
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