Kahn A, Brachet E, Conard V
C R Seances Soc Biol Fil. 1976;170(1):227-30.
Histamine, bradykinin and prostaglandin E1 increase the permeability coefficient of albumin; this effect is mimicked by dibutyryl-cAMP and by theophylline. They also cause a significant rise in the cAMP levels of the incubated tissue. Serotonin has lesser activities on these parameters. Presumably, the first three mediators control the transcellular passage of albumin by increasing the cAMP content of the tissue, serotonin being less effective. These findings on the mesentery seem to have a couterpart in vascular tissue as shown by others using different methods.
组胺、缓激肽和前列腺素E1可增加白蛋白的通透系数；二丁酰环磷腺苷和茶碱可模拟这种效应。它们还会使孵育组织中的环磷腺苷水平显著升高。血清素对这些参数的作用较小。据推测，前三种介质通过增加组织中环磷腺苷的含量来控制白蛋白的跨细胞转运，而血清素的作用较小。肠系膜上的这些发现似乎在血管组织中有对应情况，其他研究人员使用不同方法也证明了这一点。
