Su C
PUMC Hospital, Beijing.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1991 Oct;13(5):376-9.
Three cases of rare chronic hypophysitis found by surgery are reported, with a review of the related literature. Two main types of inflammatory lesions of the pituitary gland are described: lymphocytic hypophysitis (LCH) and giant-cell granulomatous hypophysitis (GGH). These present clinically as a pituitary tumor but are characterized by distinct hypopituitarism with a slightly enlarged sella turcica. Only a few cases present as hyperprolactinemia. The inflammatory process may be resolved with hormonal replacement alone for LCH, while surgical intervention is proposed for GGH.
本文报告了3例经手术发现的罕见慢性垂体炎病例,并对相关文献进行了综述。描述了垂体的两种主要炎症性病变:淋巴细胞性垂体炎(LCH)和巨细胞肉芽肿性垂体炎(GGH)。这些病变临床上表现为垂体肿瘤,但其特征是垂体功能减退伴蝶鞍轻度增大。只有少数病例表现为高催乳素血症。对于LCH,仅通过激素替代治疗炎症过程可能会得到缓解,而对于GGH则建议进行手术干预。