Hayes R P, Fitzgerald J T, Jacober S J
Global Health Outcomes, Eli Lilly and Company, Indianapolis, IN, USA.
Int J Clin Pract. 2008 Jun;62(6):860-8. doi: 10.1111/j.1742-1241.2008.01742.x. Epub 2008 Apr 3.
Insulin is the most effective drug available to achieve glycaemic goals in patients with type 2 diabetes. Yet, there is reluctance among physicians, specifically primary care physicians (PCPs) in the USA, to initiate insulin therapy in these patients.
To describe PCPs' attitudes about the initiation of insulin in patients with type 2 diabetes and identify areas in which there is a clear lack of consensus.
Primary care physicians practicing in the USA, seeing 10 or more patients with type 2 diabetes per week, and having > 3 years of clinical practice were surveyed via an internet site. The survey was developed through literature review, qualitative study and expert panel.
Primary care physicians (n = 505, mean age = 46 years, 81% male, 62% with > 10 years practice; 52% internal medicine) showed greatest consensus on attitudes regarding risk/benefits of insulin therapy, positive experiences of patients on insulin and patient fears or concerns about initiating insulin. Clear lack of consensus was seen in attitudes about the metabolic effects of insulin, need for insulin therapy, adequacy of self-monitoring blood glucose, time needed for training and potential for hypoglycaemia in elderly patients.
The beliefs of some PCPs are inconsistent with their diabetes treatment goals (HbA1c < or = 7%). Continuing medical education programmes that focus on increasing primary care physician knowledge about the progression of diabetes, the physiological effects of insulin, and tools for successfully initiating insulin in patients with type 2 diabetes are needed.
胰岛素是实现2型糖尿病患者血糖目标最有效的药物。然而,医生,尤其是美国的基层医疗医生(PCP),不太愿意对这些患者启动胰岛素治疗。
描述基层医疗医生对2型糖尿病患者启动胰岛素治疗的态度,并确定明显缺乏共识的领域。
通过一个网站对在美国执业、每周诊治10名或更多2型糖尿病患者且有超过3年临床实践经验的基层医疗医生进行调查。该调查通过文献综述、定性研究和专家小组制定。
基层医疗医生(n = 505,平均年龄 = 46岁,81%为男性,62%有超过10年的实践经验;52%为内科医生)在胰岛素治疗的风险/益处、患者使用胰岛素的积极体验以及患者对启动胰岛素的恐惧或担忧方面的态度上表现出最大的共识。在胰岛素的代谢作用、胰岛素治疗的必要性、自我血糖监测的充分性、培训所需时间以及老年患者低血糖的可能性等方面的态度上明显缺乏共识。
一些基层医疗医生的观念与他们的糖尿病治疗目标(糖化血红蛋白≤7%)不一致。需要开展继续医学教育项目,重点是增加基层医疗医生对糖尿病进展、胰岛素生理作用以及成功为2型糖尿病患者启动胰岛素治疗的工具的了解。