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神经疾病中的功能性电刺激

Functional electrical stimulation in neurological disorders.

作者信息

Sujith O K

机构信息

Pacific Parkinson's Research Center, UBC Hospital, University of British Columbia, British Columbia, Canada.

出版信息

Eur J Neurol. 2008 May;15(5):437-44. doi: 10.1111/j.1468-1331.2008.02127.x.

Abstract

Functional electrical stimulation (FES) refers to electrical stimulation of muscles in order to improve the impaired motor function. This is achieved by activating skeletal muscles with constant frequency trains of stimulations. This method has been found useful in various neurological disorders like hemiplegia, foot drop and paraplegia including spinal cord injuries. The first half of this review focuses on the broad clinical applications of functional electrical stimulation, its mechanism of action and the complications of this mode of therapy. Advanced Parkinson's disease (PD) is characterized by marked slowing of gait and frequent freezing episodes. Medical and surgical treatments are often ineffective in managing freezing episodes. The second half of this review discusses briefly the gait abnormalities in PD and the available treatment options. The possible role of FES in improving gait in parkinsonism and the importance of future research in this direction are highlighted.

摘要

功能性电刺激(FES)是指对肌肉进行电刺激,以改善受损的运动功能。这是通过用恒定频率的刺激序列激活骨骼肌来实现的。该方法已被发现对各种神经系统疾病有用,如偏瘫、足下垂和截瘫,包括脊髓损伤。本综述的前半部分重点关注功能性电刺激的广泛临床应用、其作用机制以及这种治疗方式的并发症。晚期帕金森病(PD)的特征是步态明显减慢和频繁的冻结发作。药物和手术治疗在处理冻结发作方面往往无效。本综述的后半部分简要讨论了帕金森病中的步态异常以及可用的治疗选择。强调了功能性电刺激在改善帕金森病步态方面的可能作用以及未来在这一方向研究的重要性。

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