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大脑中的联合学习信号。

Associative learning signals in the brain.

作者信息

Suzuki Wendy A

机构信息

Center for Neural Science, New York University, New York, NY 10003, USA.

出版信息

Prog Brain Res. 2008;169:305-20. doi: 10.1016/S0079-6123(07)00019-2.

DOI:10.1016/S0079-6123(07)00019-2
PMID:18394483
Abstract

Associative memory is defined as memory for the relationship between two initially unrelated items, like a name and an unfamiliar face. Associative memory is not only one of the most common forms of memory used in everyday situations, but is highly dependent on the structures of the medial temporal lobe (MTL). The goal of this chapter is to review the patterns of neural activity shown to underlie the formation of new associative memories in the MTL, as well as to examine how other extra-MTL areas participate in the learning process. Other areas implicated in various aspects of associative learning include the motor-related areas of the frontal lobe, prefrontal cortex, and striatum. The question of how the MTL and the other cortical and subcortical structures may interact during associative learning will be discussed.

摘要

关联性记忆被定义为对两个最初不相关项目之间关系的记忆,比如一个名字和一张陌生的面孔。关联性记忆不仅是日常情境中最常见的记忆形式之一,而且高度依赖于内侧颞叶(MTL)的结构。本章的目标是回顾已被证明是MTL中形成新关联性记忆基础的神经活动模式,以及研究其他MTL以外的区域如何参与学习过程。在关联性学习的各个方面涉及的其他区域包括额叶、前额叶皮质和纹状体中与运动相关的区域。将讨论在关联性学习过程中MTL与其他皮质和皮质下结构可能如何相互作用的问题。

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