Tseng Chun-Kai, Tsai Chon-Haw, Tseng Chun-Hung, Tseng Yu-Chi, Lee Fang-Yi, Huang Wei-Shih
Department of Emergency Medicine, China Medical University Hospital, Taichung, Taiwan.
Int J Hyg Environ Health. 2009 Jan;212(1):82-6. doi: 10.1016/j.ijheh.2008.01.002. Epub 2008 Apr 18.
Botulism is a rare but serious paralytic disease caused by botulinum toxin. We report an outbreak of type B botulism in Taiwan in 2006. There were five cases involved in this outbreak. They present ileus and acute cranial nerve dysfunction including dysphagia and blurred vision. One of them had severe neurologic impairment and required mechanical ventilatory support. No patient received antitoxin administration because of delayed diagnosis. The food specimen revealed positive botulism toxin B. There were no fatalities. Consumption of fermented food was significantly associated with this outbreak. We also reviewed the characteristics of cases with botulism in Taiwan since 1985.
肉毒中毒是一种由肉毒杆菌毒素引起的罕见但严重的麻痹性疾病。我们报告了2006年台湾地区B型肉毒中毒的一次暴发。此次暴发涉及5例病例。他们出现肠梗阻和急性脑神经功能障碍，包括吞咽困难和视力模糊。其中1例有严重的神经功能损害，需要机械通气支持。由于诊断延误，没有患者接受抗毒素治疗。食品样本检测出肉毒杆菌毒素B呈阳性。无死亡病例。食用发酵食品与此次暴发显著相关。我们还回顾了自1985年以来台湾地区肉毒中毒病例的特征。
