Durand J M, Lefèvre P
Department of Internal Medicine, Hôpital Sainte-Marguerite, Marseille, France.
Haematologica. 1991 Sep-Oct;76(5):421-3.
The findings and management of a patient with the mitomycin-induced syndrome of thrombotic thrombocytopenic purpura (TTP) is reported. Hyperreactivity of the cytotoxic suppressor T-cell was found. Vincristine and cyclophosphamide reversed the hematologic and renal dysfunction after administration of antiplatelet agents and plasma infusion had failed to do so.
报告了1例丝裂霉素诱发的血栓性血小板减少性紫癜（TTP）综合征患者的诊疗情况。发现细胞毒性抑制性T细胞反应过度。在给予抗血小板药物和血浆输注无效后，长春新碱和环磷酰胺逆转了血液学和肾功能障碍。
