Udayasankar U K, Braithwaite K, Arvaniti M, Tudorascu D, Small W C, Little S, Palasis S
Emory University Hospital, Atlanta, GA, USA.
AJNR Am J Neuroradiol. 2008 Apr;29(4):802-6. doi: 10.3174/ajnr.A0923.
Children with a shunt for hydrocephalus often undergo multiple follow-up head CT scans, increasing the risk for long-term effects of ionizing radiation. The purpose of our study was to evaluate if an unenhanced low-dose head CT could consistently provide acceptable image quality and diagnostic information.
Ninety-two children (mean age, 9 years; range, 8 months to 21 years; 45 boys and 47 girls) with a shunt for hydrocephalus and no clinical evidence of shunt malfunction who were referred for a follow-up nonenhanced head CT were included in the study. All studies were performed on a 4-section multidetector CT. Two CT studies were selected retrospectively for each patient, 1 performed at standard dose (220 mA) and 1 at low dose (80 mAs). Two radiologists independently evaluated and graded both standard-dose and low-dose studies for various image quality parameters. Attenuation and noise levels were measured, and gray-white differentiation and contrast-to-noise ratio (CNR) were calculated.
Low-dose CT resulted in 63% mean dose reduction. All low-dose CT scans were diagnostically acceptable. Image quality parameters were significantly lower at low dose (P = .0001) except for the parameters for streak artifacts (P = .46) and need for further imaging (P = .47), which were higher. Mean noise levels were significantly higher (P = .001) in low-dose studies, whereas CNR was significantly higher in standard dose CT (P = .001). A moderate to perfect agreement was noted between the 2 readers with regard to image quality assessment (65%-99%).
Low-dose nonenhanced head CT consistently provides diagnostically acceptable images with relevant diagnostic information in children with VP shunts resulting in substantial dose savings.
患有脑积水分流管的儿童经常接受多次头部CT随访扫描,这增加了电离辐射产生长期影响的风险。我们研究的目的是评估非增强低剂量头部CT是否能持续提供可接受的图像质量和诊断信息。
本研究纳入了92例患有脑积水分流管且无分流管故障临床证据的儿童(平均年龄9岁;范围8个月至21岁;45例男孩和47例女孩),他们因头部CT随访而被转诊。所有检查均在4层螺旋CT上进行。为每位患者回顾性选择2次CT检查,1次以标准剂量(220 mA)进行,1次以低剂量(80 mAs)进行。两名放射科医生独立评估并对标准剂量和低剂量检查的各种图像质量参数进行分级。测量衰减和噪声水平,并计算灰白质区分度和对比噪声比(CNR)。
低剂量CT使平均剂量降低了63%。所有低剂量CT扫描在诊断上均可接受。除了条纹伪影参数(P = 0.46)和进一步成像需求参数(P = 0.47)较高外,低剂量时图像质量参数显著更低(P = 0.0001)。低剂量研究中的平均噪声水平显著更高(P = 0.001),而标准剂量CT中的CNR显著更高(P = 0.001)。两位阅片者在图像质量评估方面存在中度至完全一致性(65%-99%)。
低剂量非增强头部CT能持续为患有脑室腹腔分流术的儿童提供具有相关诊断信息且在诊断上可接受的图像,从而大幅节省剂量。