钙：总钙还是离子钙？

Calcium: total or ionized?

作者信息

Schenck Patricia A, Chew Dennis J

机构信息

Endocrine Diagnostic Section, Diagnostic Center for Population and Animal Health, Department of Pathobiology and Diagnostic Investigation, Michigan State University, 4125 Beaumont Road, Lansing, MI 48910, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2008 May;38(3):497-502, ix. doi: 10.1016/j.cvsm.2008.01.010.

DOI:10.1016/j.cvsm.2008.01.010

PMID:18402876

Abstract

Measurement of serum total calcium (tCa) has been relied on for assessment of calcium status, despite the fact that it is the ionized calcium (iCa) fraction that has biologic activity. Serum tCa does not accurately predict iCa status in many clinical conditions. For accurate assessment of iCa status, iCa should be directly measured. Anaerobic measurement of serum iCa under controlled conditions provides the most reliable assessment of calcium status; aerobic measurement of iCa with species-specific pH correction is highly correlated with anaerobic measurements.

摘要

尽管具有生物活性的是离子钙（iCa）部分，但血清总钙（tCa）的测量一直被用于评估钙状态。在许多临床情况下，血清tCa并不能准确预测iCa状态。为了准确评估iCa状态，应直接测量iCa。在受控条件下对血清iCa进行厌氧测量可提供最可靠的钙状态评估；对iCa进行有氧测量并进行物种特异性pH校正与厌氧测量高度相关。