Wu Li-Tzy, Howard Matthew Owen, Pilowsky Daniel J
Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, 2218 Elder Street, 2B, DUMC Box 3419, Durham, NC 27710, USA.
Addict Behav. 2008 Jul;33(7):968-73. doi: 10.1016/j.addbeh.2008.02.019. Epub 2008 Mar 10.
To assess the prevalence, correlates, and age of onset of DSM-IV substance use disorders (SUDs) among adult inhalant users.
Analyses were based on structured psychiatric interviews of a nationally representative sample of 43,093 US adults.
The lifetime prevalence of SUDs among adult inhalant users was 96%. Alcohol (87%), marijuana (68%), nicotine (58%), cocaine (35%), hallucinogen (31%), and stimulant (28%) use disorders were more prevalent than inhalant use disorders (19%). An estimated 62% of inhalant users met criteria for a past-year SUD. Less education, residence in non-metropolitan areas, early onset of inhalant use, and a history of substance abuse treatment were associated with increased odds of having an inhalant use disorder. Inhalant users who were under age 30 or who were members of families with low incomes had increased odds of having nicotine dependence and an alcohol or drug use disorder in the past year. Compared with substance users without a history of inhalant use, inhalant users, on average, initiated use of cigarettes, alcohol, and almost all other drugs at younger ages, and had a higher lifetime prevalence of nicotine, alcohol, and any drug use disorder.
Lifetime and past-year SUDs are prevalent among adults with a history of inhalant use.
评估成年吸入剂使用者中《精神疾病诊断与统计手册》第四版(DSM-IV)物质使用障碍(SUDs)的患病率、相关因素及发病年龄。
分析基于对43,093名美国成年人的全国代表性样本进行的结构化精神病学访谈。
成年吸入剂使用者中SUDs的终生患病率为96%。酒精(87%)、大麻(68%)、尼古丁(58%)、可卡因(35%)、致幻剂(31%)和兴奋剂(28%)使用障碍比吸入剂使用障碍(19%)更为普遍。估计62%的吸入剂使用者符合过去一年SUD的标准。受教育程度较低、居住在非都市地区、较早开始使用吸入剂以及有药物滥用治疗史与吸入剂使用障碍的发生几率增加有关。30岁以下的吸入剂使用者或低收入家庭的成员在过去一年中患尼古丁依赖以及酒精或药物使用障碍的几率增加。与无吸入剂使用史的物质使用者相比,吸入剂使用者平均开始使用香烟、酒精和几乎所有其他药物的年龄更小,尼古丁、酒精和任何药物使用障碍的终生患病率更高。
有吸入剂使用史的成年人中,终生和过去一年的SUDs很普遍。