Marcinkiewicz J, Bryniarski K, Nowak B, Dzielska D, Payerhin F
Katedra Immunologii AM Krakowie.
Med Dosw Mikrobiol. 1991;43(3-4):167-74.
The influence of Acnevac vaccine on immune responses of CBA mice was tested. Acnevac, the vaccine used in a treatment of patient with acne vulgaris, was produced by a Cracow Sera and Vaccines Manufacturer from cultures of Propionibacteria-strains. It was shown that Acnevac has strong immunomodulatory properties. It strongly stimulates humoral responses, has moderate effect on cell-mediated immune responses and it also activates peritoneal macrophages to release TNF-alpha.
测试了痤疮疫苗(Acnevac)对CBA小鼠免疫反应的影响。Acnevac是一种用于治疗寻常痤疮患者的疫苗,由克拉科夫血清和疫苗制造商利用丙酸杆菌菌株培养物生产。结果表明,Acnevac具有强大的免疫调节特性。它能强烈刺激体液免疫反应,对细胞介导的免疫反应有中等作用,还能激活腹腔巨噬细胞释放肿瘤坏死因子-α。