Shankman Stewart A, Silverstein Steven M, Williams Leanne M, Hopkinson Patrick J, Kemp Andrew H, Felmingham Kim L, Bryant Richard A, McFarlane Alexander, Clark C Richard
Department of Psychology and Psychiatry, University of Illinois at Chicago, Chicago, IL 60607, USA.
J Trauma Stress. 2008 Apr;21(2):190-8. doi: 10.1002/jts.20319.
The valence-arousal (W. Heller, 1993) and approach-withdrawal (R. J. Davidson, 1998a) models hypothesize that particular patterns of hemispheric brain activity are associated with specific motivational tendencies and psychopathologies. We tested several of these predictions in two groups-a posttraumatic stress disorder (PTSD) and a "supercontrol" group, selected to be maximally different from those with PTSD. Contrary to almost all hypotheses, individuals with PTSD did not differ from controls on resting electroencephalogram (EEG) asymmetry. Particular aspects of PTSD were also not related to EEG hemisphere differences. Our null findings are consistent with the few studies that have examined resting EEG asymmetries in PTSD and suggest that PTSD may be associated with different processes than psychopathologies previously examined in studies of hemispheric brain activity (e.g., major depressive disorder, panic disorder).
效价-唤醒（W. 赫勒，1993）模型和趋近-回避（R. J. 戴维森，1998a）模型假设，特定的半球脑活动模式与特定的动机倾向和精神病理学相关。我们在两组人群中检验了其中的几个预测，一组是创伤后应激障碍（PTSD）患者，另一组是“超级对照组”，该组被选为与PTSD患者差异最大的组。与几乎所有假设相反，PTSD患者在静息脑电图（EEG）不对称性方面与对照组没有差异。PTSD的特定方面也与EEG半球差异无关。我们的阴性结果与少数研究PTSD静息EEG不对称性的研究一致，表明PTSD可能与先前在半球脑活动研究中所研究的精神病理学（如重度抑郁症、惊恐障碍）不同的过程相关。
