准备就绪的聚合酶：各就各位……预备……开始！
Poised polymerases: on your mark...get set...go!
作者信息
Price David H
机构信息
Biochemistry Department, University of Iowa, Iowa City, IA 52240, USA.
出版信息
Mol Cell. 2008 Apr 11;30(1):7-10. doi: 10.1016/j.molcel.2008.03.001.
PMID:18406322
Abstract
Recent global analyses have determined that many Drosophila and human genes have engaged polymerase molecules trapped immediately downstream of promoters. These results strongly implicate RNA polymerase II elongation control as a major regulator of differentiation and development.
摘要
近期的全球分析已确定，许多果蝇和人类基因都与被困在启动子下游紧邻位置的聚合酶分子有关。这些结果有力地表明，RNA聚合酶II延伸控制是分化和发育的主要调节因子。
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