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隐匿性丙型肝炎病毒感染在维持性血液透析患者中比乙型肝炎感染更常见。

Occult hepatitis C virus infection is more common than hepatitis B infection in maintenance hemodialysis patients.

作者信息

Jain Pankaj, Nijhawan Sandeep

出版信息

World J Gastroenterol. 2008 Apr 14;14(14):2288-9. doi: 10.3748/wjg.14.2288.

Abstract

Patients of end stage renal disease on maintenance hemodialysis were enrolled to study the prevalence of occult and dual hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and non-occult hepatitis B and C virus infection. One hundred and two patients were enrolled. Thirty patients had HCV infection, three of them were positive in anti-HCV. So, 27 (90%) of HCV-positive patients had occult HCV infection. Eleven (11%) patients had HBV infection. Five patients were positive in anti-HBc or HBV-DNA, but negative in HBsAg (occult HBV infection). Three (3%) patients had dual HBV and HCV infection. None of the patients showed changes in viral markers during the follow-up of 8 mo on average (1-12 mo).

摘要

纳入维持性血液透析的终末期肾病患者,以研究隐匿性和双重乙型肝炎病毒(HBV)及丙型肝炎病毒(HCV)感染以及非隐匿性乙型和丙型肝炎病毒感染的患病率。共纳入102例患者。30例患者感染HCV,其中3例抗-HCV阳性。因此,27例(90%)HCV阳性患者存在隐匿性HCV感染。11例(11%)患者感染HBV。5例患者抗-HBc或HBV-DNA阳性,但HBsAg阴性(隐匿性HBV感染)。3例(3%)患者同时感染HBV和HCV。平均8个月(1 - 12个月)的随访期间,所有患者的病毒标志物均未出现变化。

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