Jain Pankaj, Nijhawan Sandeep
World J Gastroenterol. 2008 Apr 14;14(14):2288-9. doi: 10.3748/wjg.14.2288.
Patients of end stage renal disease on maintenance hemodialysis were enrolled to study the prevalence of occult and dual hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and non-occult hepatitis B and C virus infection. One hundred and two patients were enrolled. Thirty patients had HCV infection, three of them were positive in anti-HCV. So, 27 (90%) of HCV-positive patients had occult HCV infection. Eleven (11%) patients had HBV infection. Five patients were positive in anti-HBc or HBV-DNA, but negative in HBsAg (occult HBV infection). Three (3%) patients had dual HBV and HCV infection. None of the patients showed changes in viral markers during the follow-up of 8 mo on average (1-12 mo).
纳入维持性血液透析的终末期肾病患者,以研究隐匿性和双重乙型肝炎病毒(HBV)及丙型肝炎病毒(HCV)感染以及非隐匿性乙型和丙型肝炎病毒感染的患病率。共纳入102例患者。30例患者感染HCV,其中3例抗-HCV阳性。因此,27例(90%)HCV阳性患者存在隐匿性HCV感染。11例(11%)患者感染HBV。5例患者抗-HBc或HBV-DNA阳性,但HBsAg阴性(隐匿性HBV感染)。3例(3%)患者同时感染HBV和HCV。平均8个月(1 - 12个月)的随访期间,所有患者的病毒标志物均未出现变化。