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本文引用的文献

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Occult hepatitis B in HIV-infected patients.HIV感染患者中的隐匿性乙型肝炎
J Acquir Immune Defic Syndr. 2004 Jul 1;36(3):869-75. doi: 10.1097/00126334-200407010-00015.
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Prevalence and clinical implications of occult hepatitis B viral infection in hemophilia patients in Japan.日本血友病患者隐匿性乙型肝炎病毒感染的患病率及临床意义
J Med Virol. 2004 Jun;73(2):195-9. doi: 10.1002/jmv.20075.
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Occult hepatitis B virus infection: implications in transfusion.隐匿性乙型肝炎病毒感染：输血中的影响。
Vox Sang. 2004 Feb;86(2):83-91. doi: 10.1111/j.0042-9007.2004.00406.x.
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Occult hepatitis B virus infection.隐匿性乙型肝炎病毒感染
Transfus Clin Biol. 2004 Feb;11(1):18-25. doi: 10.1016/j.tracli.2003.11.007.
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J Clin Virol. 2004 Mar;29(3):160-6. doi: 10.1016/S1386-6532(03)00117-3.
6
High prevalence of occult hepatitis B in Baltimore injection drug users.巴尔的摩注射吸毒者中隐匿性乙型肝炎的高流行率。
Hepatology. 2004 Jan;39(1):51-7. doi: 10.1002/hep.20025.
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Occult hepatitis B virus infection in patients with hepatocellular carcinoma: Innocent bystander, cofactor, or culprit?肝细胞癌患者中的隐匿性乙型肝炎病毒感染：无辜旁观者、辅助因子还是罪魁祸首？
Gastroenterology. 2004 Jan;126(1):347-50. doi: 10.1053/j.gastro.2003.11.021.
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Occult HBV infection and suppression of HCV replication in the early phase of combination therapy for chronic hepatitis C.隐匿性乙肝病毒感染与慢性丙型肝炎联合治疗早期丙型肝炎病毒复制的抑制
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Occult HBV infection and YMDD variants in hemodialysis patients with chronic HCV infection.慢性丙型肝炎病毒（HCV）感染血液透析患者中的隐匿性乙肝病毒（HBV）感染及YMDD变异体
J Hepatol. 2003 Apr;38(4):506-10. doi: 10.1016/s0168-8278(02)00457-9.
10
Previous hepatitis B virus infection is associated with worse disease stage and occult hepatitis B virus infection has low prevalence and pathogenicity in hepatitis C virus-positive patients.既往乙型肝炎病毒感染与更严重的疾病阶段相关，而隐匿性乙型肝炎病毒感染在丙型肝炎病毒阳性患者中的患病率和致病性较低。
Liver Int. 2003 Feb;23(1):12-8. doi: 10.1034/j.1600-0676.2003.01742.x.

慢性丙型肝炎血液透析患者隐匿性乙肝病毒感染的患病率

Prevalence of occult HBV infection in haemodialysis patients with chronic HCV.

作者信息

Goral Vedat, Ozkul Hamza, Tekes Selahattin, Sit Dede, Kadiroglu Ali Kemal

机构信息

Department of Gastroenterology, Dicle University School of Medicine, Diyarbakir, Turkey.

出版信息

World J Gastroenterol. 2006 Jun 7;12(21):3420-4. doi: 10.3748/wjg.v12.i21.3420.

DOI:10.3748/wjg.v12.i21.3420
PMID:16733862
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4087876/
Abstract

AIM

To study the prevalence and clinical effects of occult HBV infection in haemodialysis patients with chronic HCV.

METHODS

Fifty chronic hemodialysis patients with negative HbsAg, and positive anti-HCV were included in the study. These patients were divided into two groups: HCV-RNA positive and HCV-RNA negative, based on the results of HCV-RNA PCR. HBV-DNA was studied using the PCR method in both groups.

RESULTS

None of the 22 HCV-RNA positive patients and 28 HCV-RNA negative patients revealed HBV-DNA in serum by PCR method. The average age was 47.2 +/- 17.0 in the HCV-RNA positive group and 39.6 +/- 15.6 in the HCV-RNA negative group.

CONCLUSION

The prevalence of occult HBV infection is not high in haemodialysis patients with chronic HCV in our region. This result of our study has to be evaluated in consideration of the interaction between HBsAg positivity (8%-10%) and frequency of HBV mutants in our region.

摘要

目的

研究慢性丙型肝炎病毒（HCV）血液透析患者中隐匿性乙型肝炎病毒（HBV）感染的患病率及临床影响。

方法

纳入50例乙肝表面抗原（HbsAg）阴性且抗-HCV阳性的慢性血液透析患者。根据HCV-RNA聚合酶链反应（PCR）结果，将这些患者分为两组：HCV-RNA阳性组和HCV-RNA阴性组。两组均采用PCR法检测HBV-DNA。

结果

22例HCV-RNA阳性患者和28例HCV-RNA阴性患者中，通过PCR法均未在血清中检测到HBV-DNA。HCV-RNA阳性组的平均年龄为47.2±17.0岁，HCV-RNA阴性组的平均年龄为39.6±15.6岁。

结论

在我们地区，慢性HCV血液透析患者中隐匿性HBV感染的患病率不高。我们研究的这一结果必须结合我们地区HBsAg阳性率（8%-10%）和HBV突变频率之间的相互作用来评估。