Testis-determining factor and Y-linked sex reversal.
作者信息
Hawkins J R, Koopman P, Berta P
机构信息
Human Molecular Genetics Laboratory, Imperial Cancer Research Fund, London, UK.
出版信息
Curr Opin Genet Dev. 1991 Jun;1(1):30-3. doi: 10.1016/0959-437x(91)80037-m.
PMID:1840875
Abstract
A gene named SRY, isolated last year from the sex-determining region of the human Y chromosome, satisfies many of the criteria expected of the testis-determining factor gene. Mutations in SRY have been found in XY females, strongly implicating SRY as the testis-determining gene.
摘要
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