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儿童局灶性结节性增生的管理与外科治疗

Management and surgical treatment for focal nodular hyperplasia in children.

作者信息

Yang Yuan, Fu Siyuan, Li Aijun, Zhou Weiping, Pan Zeya, Cui Longjiu, Huang Gang, Wu Bowen, Wu Mengchao

机构信息

Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, #225 Changhai Road, 200438, Shanghai, China.

出版信息

Pediatr Surg Int. 2008 Jun;24(6):699-703. doi: 10.1007/s00383-008-2150-8. Epub 2008 Apr 12.

DOI:10.1007/s00383-008-2150-8
PMID:18408937
Abstract

Focal nodular hyperplasia (FNH) is rare in pediatric liver tumor. To investigate the experience in the appropriate management of pediatric FNH, the records of consecutive children who were managed at our institute from 2000 to 2007were reviewed for FNH. There were four males and nine females whose ages ranged from 26 months to 18 years with a mean of 11.7 years. FNH in most children was detected by medical examination for abdominal pain (61.5%) or other symptoms. All the 13 pediatric patients underwent liver resection. There was no operative death or postoperative complications. The children were regularly followed up ranging from 2 to 85 months and they were healthy without recurrence. For pediatric FNH patients with clinical symptoms or indefinite diagnosis, it is suggested that active surgical treatment by hepatectomy should be performed.

摘要

局灶性结节性增生(FNH)在儿童肝肿瘤中较为罕见。为探讨小儿FNH的合理治疗经验,我们回顾了2000年至2007年在我院接受治疗的连续性儿童FNH病例记录。其中男性4例,女性9例,年龄范围为26个月至18岁,平均年龄11.7岁。大多数儿童的FNH是在因腹痛(61.5%)或其他症状进行体格检查时发现的。所有13例小儿患者均接受了肝切除术。无手术死亡或术后并发症发生。对患儿进行了2至85个月的定期随访,他们均健康无复发。对于有临床症状或诊断不明确的小儿FNH患者,建议积极行肝切除术进行手术治疗。

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Molecular pathogenesis of focal nodular hyperplasia and hepatocellular adenoma.局灶性结节性增生和肝细胞腺瘤的分子发病机制。
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Management and algorithm for focal nodular hyperplasia of the liver in children.儿童肝脏局灶性结节性增生的管理与诊疗流程
病例报告:9岁女童局灶性结节性增生的超声引导下经皮微波消融术
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