[术后镇痛药物：常规与新进展：第2部分：阿片类药物、氯胺酮和加巴喷丁类药物]
[Drugs for postoperative analgesia: routine and new aspects: Part 2: opioids, ketamine and gabapentinoids].
作者信息
Jage J, Laufenberg-Feldmann R, Heid F
机构信息
Klinik für Anästhesiologie, Johannes Gutenberg-Universität, Langenbeckstr. 1, 55131 Mainz.
出版信息
Anaesthesist. 2008 May;57(5):491-8. doi: 10.1007/s00101-008-1327-9.
In part 1 of this review, perioperative aspects of the use of non-opioids (acetaminophene, dipyrone, traditional NSAR, coxibs) were discussed. In part 2 the perioperative aspects of opioids (weak opioids: tramadol, tilidine with naloxone, strong opioids: morphine, piritramide, oxycodone, hydromorphone, fentanyl, methadone, buprenorphine) and coanalgesics (gabapentinoids; ketamine) will now be presented. The main aim of the review is to describe the use, risks and cost of some substances to facilitate the differential indication. New aspects concerning the use of gabapentinoids and ketamine are discussed.
在本综述的第1部分，讨论了非阿片类药物（对乙酰氨基酚、安乃近、传统非甾体类抗炎药、环氧化酶-2抑制剂）的围手术期应用情况。在第2部分，将阐述阿片类药物（弱阿片类药物：曲马多、纳洛酮复合蒂巴因、强阿片类药物：吗啡、匹利卡明、羟考酮、氢吗啡酮、芬太尼、美沙酮、丁丙诺啡）和辅助镇痛药（加巴喷丁类药物；氯胺酮）的围手术期应用情况。本综述的主要目的是描述某些药物的使用方法、风险和成本，以促进鉴别诊断。还讨论了加巴喷丁类药物和氯胺酮使用方面的新情况。
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