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[橡胶工业与致癌化学物质暴露:意大利伦巴第地区的多中心研究]

[Rubber industry and exposure to carcinogenic chemical agents: an Italian Multicentric Study in Lombardy].

作者信息

Cirla P E, Tieghi S, Trinco R, Galli L, Filipponi A, Pavesi D, Martinotti I, Foà V, Cirla A M, Mossini E

机构信息

Università degli Studi di Milano e Fondazione "Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena" (IRCCS), Dipartimento di Medicina del Lavoro, Milano.

出版信息

G Ital Med Lav Ergon. 2007 Jul-Sep;29(3 Suppl):317-9.

PMID:18409704
Abstract

Evaluating the chemical risks at the workplaces, the potential carcinogenic risk is a primary interest. Particularly, in the rubber forming industry the main attention was directed to the hot processing as a possible source of exposure to chemical agents, several of which were classified as carcinogens by the International Agency for Research on Cancer (IARC) and/or the European Union (EU). A study on occupational exposure to chemical carcinogens in the rubber forming industry was planned during last two years, involving a representative sample of firms. In the first step the occupational exposure and the use of preventive measures were evaluated by an investigation at workplace supported with standardized questionnaires. The presence of above 100 chemical agents was registered; 15 agents were classified to carcinogenic or probably carcinogenic to human. The evaluation of exposure by air sampling and monitoring of most substances of interest (acrylonitrile, 1,3-butadiene, styrene, Polycyclic Aromatic Hydrocarbons), demonstrated a low level of occupational exposure, the common hygienic prevention measure being applied.

摘要

在评估工作场所的化学风险时,潜在致癌风险是主要关注点。特别是在橡胶成型行业,主要注意力集中在热加工上,因为它可能是接触化学物质的一个来源,其中有几种化学物质被国际癌症研究机构(IARC)和/或欧盟(EU)列为致癌物。在过去两年中,计划对橡胶成型行业职业接触化学致癌物的情况进行一项研究,涉及具有代表性的企业样本。第一步,通过在工作场所进行调查并辅以标准化问卷,对职业接触情况和预防措施的使用进行评估。登记了100多种化学物质的存在;有15种物质被归类为对人类致癌或可能致癌。通过对大多数相关物质(丙烯腈、1,3 - 丁二烯、苯乙烯、多环芳烃)进行空气采样和监测来评估接触情况,结果表明职业接触水平较低,并且采用了常见的卫生预防措施。

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