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[塑料行业与致癌化学物质暴露:意大利伦巴第大区多中心研究]

[Plastic industry and exposure to carcinogenic chemical agents: an Italian Multicentric Study in Lombardy].

作者信息

Cirla P E, Castoldi M R, Marchese E, Cavallo D M, Fustinoni S, Cattaneo A, Martinotti I, Foà V, Tiso C

机构信息

Università degli Studi di Milano e Fondazione "Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena" (IRCCS), Dipartimento di Medicina del Lavoro, Milano.

出版信息

G Ital Med Lav Ergon. 2007 Jul-Sep;29(3 Suppl):319-21.

PMID:18409705
Abstract

The potential carcinogenic risk at the workplaces is a primary interest of occupational health, but some questions are also controversially discussed. Particularly, in the plastic forming industry a great attention was directed to the hot processing and their possible exposure to monomers, some of which were classified as carcinogen by the International Agency for Research on Cancer (IARC) and/or the European Union (EU). In Lombardy, a study on occupational exposure to chemical carcinogens in the plastic forming industry was planned during last years. The aim was to recognize and promote preventive technical and medical solutions, basing on efficacy. By an investigation at workplace supported with standardized questionnaires, the presence of chemical carcinogens was registered in 59% of a representative sample of firms; but an effective possibility of exposure was found only for 34% of cases. The evaluation of exposure to monomers by air monitoring (acrylonitrile, 1,3-butadiene, styrene, formaldehyde), involving a representative sample of factory with ABS and formaldehydic resins processing, showed low level exposure, because the common hygienic prevention measures were applied; some particular occupation shoved greater exposure to formaldehyde.

摘要

工作场所的潜在致癌风险是职业健康的主要关注点,但一些问题也存在争议性讨论。特别是在塑料成型行业,人们高度关注热加工过程以及工人可能接触到的单体,其中一些单体被国际癌症研究机构(IARC)和/或欧盟(EU)列为致癌物。在伦巴第大区,过去几年计划开展一项关于塑料成型行业职业接触化学致癌物的研究。其目的是基于有效性识别并推广预防性技术和医疗解决方案。通过在工作场所进行的调查,并辅以标准化问卷,在具有代表性的企业样本中,59%的企业检测到了化学致癌物的存在;但仅在34%的案例中发现了实际的接触可能性。对涉及使用ABS和甲醛树脂加工的代表性工厂样本进行空气监测(丙烯腈、1,3 - 丁二烯、苯乙烯、甲醛)以评估单体接触情况,结果显示接触水平较低,因为采取了常规的卫生预防措施;一些特定职业显示出更高的甲醛接触水平。

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